Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3027153..3027799 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NLZ15_RS14270 Protein ID WP_254486466.1
Coordinates 3027446..3027799 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NLZ15_RS14265 Protein ID WP_125291701.1
Coordinates 3027153..3027449 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS14255 (NLZ15_14255) 3024792..3025646 - 855 WP_254486465.1 DNA-3-methyladenine glycosylase 2 -
NLZ15_RS14260 (NLZ15_14260) 3025778..3027130 + 1353 WP_254489029.1 molecular chaperone -
NLZ15_RS14265 (NLZ15_14265) 3027153..3027449 - 297 WP_125291701.1 XRE family transcriptional regulator Antitoxin
NLZ15_RS14270 (NLZ15_14270) 3027446..3027799 - 354 WP_254486466.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLZ15_RS14275 (NLZ15_14275) 3028027..3029253 + 1227 WP_254486467.1 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit -
NLZ15_RS14280 (NLZ15_14280) 3029253..3032375 + 3123 WP_144130447.1 MdtB/MuxB family multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-80)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13794.97 Da        Isoelectric Point: 10.1483

>T250647 WP_254486466.1 NZ_CP100494:c3027799-3027446 [Atlantibacter subterranea]
MTWTVVFTPEFEQWLYDQEPGLKNRVNAALLTLELTGPALGRPRVDTLFGSFYPNMKELRLQYAGDPWRICFAFDYSRQA
IMLYGGKKTGQKRFYRTLITRVDAIFARYLARKKDRE

Download         Length: 354 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10925.51 Da        Isoelectric Point: 4.9512

>AT250647 WP_125291701.1 NZ_CP100494:c3027449-3027153 [Atlantibacter subterranea]
MKTLQQHLAELTPEHRAEIERLAEEFAAENGLPTIREMRAMSQQELAERLGVTQPAVAAMERRGDDIKVSTLKRYAEALG
GELKISIELPEGSRVISL

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References