250640

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 159568..160913 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag NLZ15_RS00755 Protein ID WP_254487513.1
Coordinates 159879..160913 (+) Length 345 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag NLZ15_RS00750 Protein ID WP_125292711.1
Coordinates 159568..159879 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS00725 (NLZ15_00725) 155129..156148 + 1020 WP_125292718.1 dipeptide ABC transporter permease DppB -
NLZ15_RS00730 (NLZ15_00730) 156158..157060 + 903 WP_125292716.1 dipeptide ABC transporter permease DppC -
NLZ15_RS00735 (NLZ15_00735) 157072..158064 + 993 WP_151602793.1 dipeptide ABC transporter ATP-binding protein -
NLZ15_RS00740 (NLZ15_00740) 158051..159061 + 1011 WP_125292713.1 dipeptide ABC transporter ATP-binding subunit DppF -
NLZ15_RS00745 (NLZ15_00745) 159260..159583 + 324 WP_254487512.1 helix-turn-helix domain-containing protein -
NLZ15_RS00750 (NLZ15_00750) 159568..159879 + 312 WP_125292711.1 HipA N-terminal domain-containing protein Antitoxin
NLZ15_RS00755 (NLZ15_00755) 159879..160913 + 1035 WP_254487513.1 HipA domain-containing protein Toxin
NLZ15_RS00760 (NLZ15_00760) 160966..161157 - 192 WP_144131794.1 toxin-antitoxin system HicB family antitoxin -
NLZ15_RS00765 (NLZ15_00765) 161291..161821 + 531 WP_125292708.1 hypothetical protein -
NLZ15_RS00770 (NLZ15_00770) 161903..162193 + 291 WP_151602785.1 DUF1778 domain-containing protein -
NLZ15_RS00775 (NLZ15_00775) 162172..162711 + 540 WP_254487514.1 GNAT family N-acetyltransferase -
NLZ15_RS00780 (NLZ15_00780) 162756..163256 - 501 WP_125292940.1 poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD -
NLZ15_RS00785 (NLZ15_00785) 163259..164587 - 1329 WP_125292705.1 poly-beta-1,6-N-acetyl-D-glucosamine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(56-306)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 345 a.a.        Molecular weight: 38611.23 Da        Isoelectric Point: 6.6972

>T250640 WP_254487513.1 NZ_CP100494:159879-160913 [Atlantibacter subterranea]
MANCRISLTPLHPRDEATGYSSRGLKQLTGNGRADPQLPFSRSEFIAELPKTQAGMSISGYQPKLQVVQQNGAFNVVNHQ
GDYILKPSPAEFPFLAENEHATMTLMSRLGFAVPPHGLVRFANTQPGDADEYAFIVRRFDRDAQGKALHQEQLDAAMNVG
EKYGKIREDGKQYVSYQQLAEFLLAHVNDNLAFKIDLFRRIAYAYLLGNNDMHLRNFGLILPVEGAPELAPVYDFVSVAP
YPAAFNRGFLALPLLRCEEGEQDLAPGMKTQYGEYLGKDFLLLGEAMGLARAVVLRLFAQMQKEAVTVEKVYRASFMPES
DVARVLQCYRYRLHRIMNVDVVEL

Download         Length: 1035 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11804.45 Da        Isoelectric Point: 6.7163

>AT250640 WP_125292711.1 NZ_CP100494:159568-159879 [Atlantibacter subterranea]
MHRRVTVLLYGEPVGELVQEATGFRFTYRDDYQGPPLSLSLPVSQRTFHCTTLHPFFVSLAPEGWLRNRYSQLQQRDEKD
LLGMLIDNGKNLIGAVQIRAEEA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References