Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2079904..2080423 Replicon chromosome
Accession NZ_CP100326
Organism Streptococcus suis strain STC90

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0K2E7Z7
Locus tag NKZ63_RS10380 Protein ID WP_013730620.1
Coordinates 2079904..2080161 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0K2E7Z9
Locus tag NKZ63_RS10385 Protein ID WP_002939010.1
Coordinates 2080163..2080423 (-) Length 87 a.a.

Genomic Context

NKZ63_RS10365NKZ63_RS10370NKZ63_RS10375NKZ63_RS10380NKZ63_RS10385NKZ63_RS10390NKZ63_RS10395NKZ63_RS10400NKZ63_RS10405NKZ63_RS10410NKZ63_RS10415NKZ63_RS10420NKZ63_RS10425
Location: 2076374..2078104 (1731 bp)
Type: Others
Protein ID: WP_024417308.1
Location: 2078468..2079340 (873 bp)
Type: Others
Protein ID: WP_024393352.1
Location: 2079360..2079890 (531 bp)
Type: Others
Protein ID: WP_009910909.1
Location: 2079904..2080161 (258 bp)
Type: Toxin
Protein ID: WP_013730620.1
Location: 2080163..2080423 (261 bp)
Type: Antitoxin
Protein ID: WP_002939010.1
Location: 2080499..2080954 (456 bp)
Type: Others
Protein ID: WP_024417307.1
Location: 2080959..2081327 (369 bp)
Type: Others
Protein ID: WP_024417306.1
Location: 2081320..2081889 (570 bp)
Type: Others
Protein ID: WP_024417305.1
Location: 2081873..2082655 (783 bp)
Type: Others
Protein ID: WP_024417304.1
Location: 2082762..2082899 (138 bp)
Type: Others
Protein ID: WP_002939016.1
Location: 2083067..2084062 (996 bp)
Type: Others
Protein ID: WP_013730624.1
Location: 2084082..2084894 (813 bp)
Type: Others
Protein ID: WP_012027897.1
Location: 2084878..2085237 (360 bp)
Type: Others
Protein ID: WP_004194560.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NKZ63_RS10365 (NKZ63_10365)2076374..2078104-1731WP_024417308.1membrane protein-
NKZ63_RS10370 (NKZ63_10370)2078468..2079340-873WP_024393352.116S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA-
NKZ63_RS10375 (NKZ63_10375)2079360..2079890-531WP_009910909.1DUF1697 domain-containing protein-
NKZ63_RS10380 (NKZ63_10380)2079904..2080161-258WP_013730620.1Txe/YoeB family addiction module toxinToxin
NKZ63_RS10385 (NKZ63_10385)2080163..2080423-261WP_002939010.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
NKZ63_RS10390 (NKZ63_10390)2080499..2080954-456WP_024417307.18-oxo-dGTP diphosphatase-
NKZ63_RS10395 (NKZ63_10395)2080959..2081327-369WP_024417306.1hypothetical protein-
NKZ63_RS10400 (NKZ63_10400)2081320..2081889-570WP_024417305.1ribonuclease M5-
NKZ63_RS10405 (NKZ63_10405)2081873..2082655-783WP_024417304.1TatD family hydrolase-
NKZ63_RS10410 (NKZ63_10410)2082762..2082899-138WP_002939016.150S ribosomal protein L34-
NKZ63_RS10415 (NKZ63_10415)2083067..2084062-996WP_013730624.1RNA-binding cell elongation regulator Jag/EloR-
NKZ63_RS10420 (NKZ63_10420)2084082..2084894-813WP_012027897.1YidC/Oxa1 family membrane protein insertase-
NKZ63_RS10425 (NKZ63_10425)2084878..2085237-360WP_004194560.1ribonuclease P protein component-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10346.86 Da        Isoelectric Point: 8.0279

>T250444 WP_013730620.1 NZ_CP100326:c2080161-2079904 [Streptococcus suis]
MGIHFTDDAWEDYLYWQGQDKKTLKRINKIIKDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEADRLCILSL
KDHYR

Download         Length: 258 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9980.36 Da        Isoelectric Point: 5.7134

>AT250444 WP_002939010.1 NZ_CP100326:c2080423-2080163 [Streptococcus suis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAKVKTGQTQER
NLIEAD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0K2E7Z7

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0K2E7Z9

References