Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 41942..42600 Replicon plasmid unnamed1
Accession NZ_CP100306
Organism Acinetobacter baumannii strain KBN10P05679

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NIK71_RS19630 Protein ID WP_000312250.1
Coordinates 42241..42600 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NIK71_RS19625 Protein ID WP_001096429.1
Coordinates 41942..42241 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIK71_RS19580 (NIK71_19580) 36975..37232 + 258 WP_000834292.1 hypothetical protein -
NIK71_RS19585 (NIK71_19585) 37237..37809 + 573 WP_000429351.1 hypothetical protein -
NIK71_RS19590 (NIK71_19590) 37785..37964 + 180 WP_002081921.1 hypothetical protein -
NIK71_RS19595 (NIK71_19595) 37981..38610 + 630 WP_002081923.1 hypothetical protein -
NIK71_RS19600 (NIK71_19600) 38650..39159 + 510 WP_001043199.1 hypothetical protein -
NIK71_RS19605 (NIK71_19605) 39240..39794 + 555 WP_000790085.1 hypothetical protein -
NIK71_RS19610 (NIK71_19610) 39844..40380 + 537 WP_000731981.1 hypothetical protein -
NIK71_RS19615 (NIK71_19615) 41003..41485 + 483 WP_001052677.1 hypothetical protein -
NIK71_RS19620 (NIK71_19620) 41578..41841 - 264 WP_000110863.1 hypothetical protein -
NIK71_RS19625 (NIK71_19625) 41942..42241 - 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
NIK71_RS19630 (NIK71_19630) 42241..42600 - 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NIK71_RS19635 (NIK71_19635) 42801..43367 + 567 WP_041171756.1 hypothetical protein -
NIK71_RS19640 (NIK71_19640) 43416..43598 + 183 WP_000373385.1 hypothetical protein -
NIK71_RS19645 (NIK71_19645) 43665..44363 + 699 WP_000873190.1 hypothetical protein -
NIK71_RS19650 (NIK71_19650) 44502..44885 + 384 WP_000654349.1 hypothetical protein -
NIK71_RS19655 (NIK71_19655) 44952..45710 + 759 WP_001053129.1 hypothetical protein -
NIK71_RS19660 (NIK71_19660) 46778..47092 + 315 WP_000708714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..74294 74294


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T250403 WP_000312250.1 NZ_CP100306:c42600-42241 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT250403 WP_001096429.1 NZ_CP100306:c42241-41942 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References