Detailed information of TA system TA250029

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 981278..981537
• Replicon: chromosome
• Accession: NZ_CP099990
• Organism: Staphylococcus equorum strain PU1

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: NHN23_RS04675
• Protein ID: WP_002511402.1
• Coordinates: 981278..981385 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	981375..981537 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NHN23_RS04645	976510..977382	+	873	WP_002507156.1	ABC transporter ATP-binding protein	-
NHN23_RS04650	977382..978110	+	729	WP_002507157.1	ABC transporter permease subunit	-
NHN23_RS04655	978193..978753	-	561	WP_002507158.1	thioredoxin family protein	-
NHN23_RS04660	978969..979409	+	441	WP_231111012.1	hypothetical protein	-
NHN23_RS04665	979504..980064	+	561	WP_002511403.1	DUF1700 domain-containing protein	-
NHN23_RS04670	980061..980912	+	852	WP_253345685.1	DUF4097 family beta strand repeat-containing protein	-
NHN23_RS04675	981278..981385	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	981375..981537	-	163	-	-	Antitoxin
NHN23_RS04680	981673..981843	-	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
NHN23_RS04685	982151..983191	-	1041	WP_021339984.1	C45 family autoproteolytic acyltransferase/hydolase	-
NHN23_RS04690	983686..983856	+	171	WP_002507168.1	hypothetical protein	-
NHN23_RS04695	984250..984660	-	411	WP_002507169.1	YolD-like family protein	-
NHN23_RS04700	984837..985874	+	1038	WP_021339833.1	lactonase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T250029 WP_002511402.1 NZ_CP099990:981278-981385 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 163 bp

>AT250029 NZ_CP099990:c981537-981375 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin