Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4018743..4019001 Replicon chromosome
Accession NZ_CP099907
Organism Escherichia albertii strain 112_1_EW_A

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag NIY89_RS19645 Protein ID WP_000809168.1
Coordinates 4018849..4019001 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4018743..4018800 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY89_RS19630 4014550..4015797 - 1248 WP_059224806.1 hypothetical protein -
NIY89_RS19635 4015951..4017444 - 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
NIY89_RS19640 4017465..4018226 - 762 WP_001276206.1 outer membrane protein OmpK -
- 4018743..4018800 - 58 - - Antitoxin
NIY89_RS19645 4018849..4019001 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
NIY89_RS19650 4019109..4020239 - 1131 WP_001118445.1 molecular chaperone DnaJ -
NIY89_RS19655 4020328..4022244 - 1917 WP_000516137.1 molecular chaperone DnaK -
NIY89_RS19660 4022619..4023023 + 405 WP_000833521.1 DUF2541 family protein -
NIY89_RS19665 4023050..4023763 + 714 WP_059224803.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T249905 WP_000809168.1 NZ_CP099907:4018849-4019001 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT249905 NZ_CP099907:c4018800-4018743 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References