Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3935242..3935500 Replicon chromosome
Accession NZ_CP099906
Organism Escherichia albertii strain 121_1_EW_A

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag NIY90_RS19075 Protein ID WP_000809168.1
Coordinates 3935242..3935394 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3935443..3935500 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY90_RS19055 3930480..3931193 - 714 WP_001102345.1 acidic protein MsyB -
NIY90_RS19060 3931220..3931624 - 405 WP_000833521.1 DUF2541 family protein -
NIY90_RS19065 3931999..3933915 + 1917 WP_000516135.1 molecular chaperone DnaK -
NIY90_RS19070 3934004..3935134 + 1131 WP_001118445.1 molecular chaperone DnaJ -
NIY90_RS19075 3935242..3935394 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3935443..3935500 + 58 - - Antitoxin
NIY90_RS19080 3936016..3936777 + 762 WP_105198098.1 outer membrane protein OmpK -
NIY90_RS19085 3936798..3938291 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
NIY90_RS19090 3938445..3939692 + 1248 WP_059224806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T249887 WP_000809168.1 NZ_CP099906:c3935394-3935242 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT249887 NZ_CP099906:3935443-3935500 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References