Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2052272..2052517 Replicon chromosome
Accession NZ_CP099906
Organism Escherichia albertii strain 121_1_EW_A

Toxin (Protein)


Gene name hokX Uniprot ID L4J2K8
Locus tag NIY90_RS10125 Protein ID WP_000956460.1
Coordinates 2052272..2052424 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 2052469..2052517 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY90_RS10100 2047540..2047863 - 324 WP_001246114.1 DUF3561 family protein -
NIY90_RS10105 2047913..2048518 - 606 WP_256878896.1 adenylyl-sulfate kinase -
NIY90_RS10110 2048518..2049945 - 1428 WP_054412002.1 sulfate adenylyltransferase subunit CysN -
NIY90_RS10115 2049947..2050855 - 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
NIY90_RS10120 2051109..2052146 + 1038 WP_256878880.1 alkaline phosphatase isozyme conversion aminopeptidase -
NIY90_RS10125 2052272..2052424 - 153 WP_000956460.1 Hok/Gef family protein Toxin
- 2052469..2052517 + 49 - - Antitoxin
NIY90_RS10130 2052688..2053422 - 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
NIY90_RS10135 2053602..2055314 - 1713 WP_161538126.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
NIY90_RS10140 2055314..2057113 - 1800 WP_256878879.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5602.81 Da        Isoelectric Point: 7.7899

>T249875 WP_000956460.1 NZ_CP099906:c2052424-2052272 [Escherichia albertii]
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT249875 NZ_CP099906:2052469-2052517 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G7J5

Antitoxin

Download structure file

References