Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1054186..1054432 Replicon chromosome
Accession NZ_CP099903
Organism Escherichia albertii strain 133_1_GWG_A

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag NIY95_RS05020 Protein ID WP_000956458.1
Coordinates 1054280..1054432 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1054186..1054238 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY95_RS05005 1049590..1051389 + 1800 WP_233991385.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
NIY95_RS05010 1051389..1053101 + 1713 WP_059224425.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
NIY95_RS05015 1053281..1054015 + 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
- 1054186..1054238 - 53 - - Antitoxin
NIY95_RS05020 1054280..1054432 + 153 WP_000956458.1 Hok/Gef family protein Toxin
NIY95_RS05025 1054558..1055595 - 1038 WP_059225076.1 alkaline phosphatase isozyme conversion aminopeptidase -
NIY95_RS05030 1055848..1056756 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
NIY95_RS05035 1056758..1058185 + 1428 WP_137648822.1 sulfate adenylyltransferase subunit CysN -
NIY95_RS05040 1058185..1058790 + 606 WP_024164730.1 adenylyl-sulfate kinase -
NIY95_RS05045 1058840..1059163 + 324 WP_044711292.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T249843 WP_000956458.1 NZ_CP099903:1054280-1054432 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT249843 NZ_CP099903:c1054238-1054186 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References