Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3882386..3882644 Replicon chromosome
Accession NZ_CP099898
Organism Escherichia albertii strain 147_1_TBG_A

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag NIZ13_RS18935 Protein ID WP_000809168.1
Coordinates 3882492..3882644 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3882386..3882443 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ13_RS18920 3878193..3879440 - 1248 WP_059235056.1 hypothetical protein -
NIZ13_RS18925 3879594..3881087 - 1494 WP_256875787.1 sulfatase-like hydrolase/transferase -
NIZ13_RS18930 3881108..3881869 - 762 WP_001276206.1 outer membrane protein OmpK -
- 3882386..3882443 - 58 - - Antitoxin
NIZ13_RS18935 3882492..3882644 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
NIZ13_RS18940 3882752..3883882 - 1131 WP_001118445.1 molecular chaperone DnaJ -
NIZ13_RS18945 3883971..3885887 - 1917 WP_000516135.1 molecular chaperone DnaK -
NIZ13_RS18950 3886262..3886666 + 405 WP_000833521.1 DUF2541 family protein -
NIZ13_RS18955 3886693..3887406 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T249829 WP_000809168.1 NZ_CP099898:3882492-3882644 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT249829 NZ_CP099898:c3882443-3882386 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References