Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 2437631..2438430 Replicon chromosome
Accession NZ_CP099890
Organism Escherichia albertii strain 205_2_TBG_B

Toxin (Protein)


Gene name yhaV Uniprot ID A0A8H9C2I0
Locus tag NIZ17_RS12200 Protein ID WP_059227548.1
Coordinates 2437631..2438095 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag NIZ17_RS12205 Protein ID WP_060877482.1
Coordinates 2438095..2438430 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ17_RS12170 (2432632) 2432632..2433066 - 435 WP_149451364.1 PTS galactosamine/N-acetylgalactosamine transporter subunit IIA -
NIZ17_RS12175 (2433084) 2433084..2433962 - 879 WP_001295548.1 PTS N-acetylgalactosamine transporter subunit IID -
NIZ17_RS12180 (2433952) 2433952..2434731 - 780 WP_000406226.1 PTS N-acetylgalactosamine transporter subunit IIC -
NIZ17_RS12185 (2434742) 2434742..2435215 - 474 WP_002461030.1 PTS N-acetylgalactosamine transporter subunit IIB -
NIZ17_RS12190 (2435238) 2435238..2436518 - 1281 WP_059235447.1 tagatose-bisphosphate aldolase subunit KbaZ -
NIZ17_RS12195 (2436767) 2436767..2437576 + 810 WP_000072169.1 aga operon transcriptional regulator AgaR -
NIZ17_RS12200 (2437631) 2437631..2438095 - 465 WP_059227548.1 type II toxin-antitoxin system ribonuclease toxin YhaV Toxin
NIZ17_RS12205 (2438095) 2438095..2438430 - 336 WP_060877482.1 type II toxin-antitoxin system antitoxin PrlF Antitoxin
NIZ17_RS12210 (2438579) 2438579..2440150 - 1572 WP_256879795.1 galactarate dehydratase -
NIZ17_RS12215 (2440521) 2440521..2441855 + 1335 WP_000599659.1 galactarate/glucarate/glycerate transporter GarP -
NIZ17_RS12220 (2441871) 2441871..2442641 + 771 WP_025238278.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17819.26 Da        Isoelectric Point: 9.7301

>T249756 WP_059227548.1 NZ_CP099890:c2438095-2437631 [Escherichia albertii]
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRFRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTQETEEKH

Download         Length: 465 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12320.93 Da        Isoelectric Point: 4.6672

>AT249756 WP_060877482.1 NZ_CP099890:c2438430-2438095 [Escherichia albertii]
MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHYEILPGGQVFMCRLGDEQENHTMNAFLRFLDADIQNN
PQKTRPFDIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References