Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3281331..3281577 Replicon chromosome
Accession NZ_CP099883
Organism Escherichia albertii strain 231_1_NP_B

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag NIZ20_RS16055 Protein ID WP_000956458.1
Coordinates 3281331..3281483 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 3281525..3281577 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ20_RS16030 3276600..3276923 - 324 WP_044711292.1 DUF3561 family protein -
NIZ20_RS16035 3276973..3277578 - 606 WP_024164730.1 adenylyl-sulfate kinase -
NIZ20_RS16040 3277578..3279005 - 1428 WP_137648822.1 sulfate adenylyltransferase subunit CysN -
NIZ20_RS16045 3279007..3279915 - 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
NIZ20_RS16050 3280168..3281205 + 1038 WP_059225076.1 alkaline phosphatase isozyme conversion aminopeptidase -
NIZ20_RS16055 3281331..3281483 - 153 WP_000956458.1 Hok/Gef family protein Toxin
- 3281525..3281577 + 53 - - Antitoxin
NIZ20_RS16060 3281748..3282482 - 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
NIZ20_RS16065 3282662..3284374 - 1713 WP_059224425.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
NIZ20_RS16070 3284374..3286173 - 1800 WP_233991385.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T249682 WP_000956458.1 NZ_CP099883:c3281483-3281331 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT249682 NZ_CP099883:3281525-3281577 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References