Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 325451..325709 Replicon chromosome
Accession NZ_CP099883
Organism Escherichia albertii strain 231_1_NP_B

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag NIZ20_RS01545 Protein ID WP_000809168.1
Coordinates 325451..325603 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 325652..325709 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ20_RS01525 320689..321402 - 714 WP_059224803.1 acidic protein MsyB -
NIZ20_RS01530 321429..321833 - 405 WP_000833521.1 DUF2541 family protein -
NIZ20_RS01535 322208..324124 + 1917 WP_000516137.1 molecular chaperone DnaK -
NIZ20_RS01540 324213..325343 + 1131 WP_001118445.1 molecular chaperone DnaJ -
NIZ20_RS01545 325451..325603 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 325652..325709 + 58 - - Antitoxin
NIZ20_RS01550 326226..326987 + 762 WP_001276206.1 outer membrane protein OmpK -
NIZ20_RS01555 327008..328501 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
NIZ20_RS01560 328655..329902 + 1248 WP_059224806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T249669 WP_000809168.1 NZ_CP099883:c325603-325451 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT249669 NZ_CP099883:325652-325709 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References