Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1054016..1054262 Replicon chromosome
Accession NZ_CP099880
Organism Escherichia albertii strain 233_2_GWG_B

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag NIZ21_RS05020 Protein ID WP_000956458.1
Coordinates 1054110..1054262 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1054016..1054068 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ21_RS05005 1049420..1051219 + 1800 WP_233991385.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
NIZ21_RS05010 1051219..1052931 + 1713 WP_059224425.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
NIZ21_RS05015 1053111..1053845 + 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
- 1054016..1054068 - 53 - - Antitoxin
NIZ21_RS05020 1054110..1054262 + 153 WP_000956458.1 Hok/Gef family protein Toxin
NIZ21_RS05025 1054388..1055425 - 1038 WP_059225076.1 alkaline phosphatase isozyme conversion aminopeptidase -
NIZ21_RS05030 1055678..1056586 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
NIZ21_RS05035 1056588..1058015 + 1428 WP_137648822.1 sulfate adenylyltransferase subunit CysN -
NIZ21_RS05040 1058015..1058620 + 606 WP_024164730.1 adenylyl-sulfate kinase -
NIZ21_RS05045 1058670..1058993 + 324 WP_044711292.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T249640 WP_000956458.1 NZ_CP099880:1054110-1054262 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT249640 NZ_CP099880:c1054068-1054016 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References