Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1093882..1094127 Replicon chromosome
Accession NZ_CP099874
Organism Escherichia albertii strain 251_2_EW_B

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag NIZ23_RS05255 Protein ID WP_000956458.1
Coordinates 1093975..1094127 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1093882..1093930 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ23_RS05240 1089286..1091085 + 1800 WP_059241923.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
NIZ23_RS05245 1091085..1092797 + 1713 WP_256875819.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
NIZ23_RS05250 1092977..1093711 + 735 WP_059235904.1 phosphoadenosine phosphosulfate reductase -
- 1093882..1093930 - 49 - - Antitoxin
NIZ23_RS05255 1093975..1094127 + 153 WP_000956458.1 Hok/Gef family protein Toxin
NIZ23_RS05260 1094252..1095289 - 1038 WP_059235902.1 alkaline phosphatase isozyme conversion aminopeptidase -
NIZ23_RS05265 1095543..1096451 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
NIZ23_RS05270 1096453..1097880 + 1428 WP_256875818.1 sulfate adenylyltransferase subunit CysN -
NIZ23_RS05275 1097880..1098485 + 606 WP_024164730.1 adenylyl-sulfate kinase -
NIZ23_RS05280 1098535..1098858 + 324 WP_001246114.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T249594 WP_000956458.1 NZ_CP099874:1093975-1094127 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT249594 NZ_CP099874:c1093930-1093882 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References