Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symER/SymE(toxin)
Location 3989853..3990265 Replicon chromosome
Accession NZ_CP099871
Organism Escherichia albertii strain 253_2_EW_B

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag NIZ24_RS19400 Protein ID WP_256878049.1
Coordinates 3989924..3990265 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name symR
Locus tag -
Coordinates 3989853..3989929 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ24_RS19390 (3986737) 3986737..3988326 + 1590 WP_256878047.1 type I restriction-modification system methyltransferase -
NIZ24_RS19395 (3988323) 3988323..3989696 + 1374 WP_256878048.1 restriction endonuclease subunit S -
- (3989853) 3989853..3989929 - 77 NuclAT_8 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_8 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_8 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_8 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_9 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_9 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_9 - Antitoxin
- (3989853) 3989853..3989929 - 77 NuclAT_9 - Antitoxin
NIZ24_RS19400 (3989924) 3989924..3990265 + 342 WP_256878049.1 endoribonuclease SymE Toxin
NIZ24_RS19405 (3990312) 3990312..3991478 - 1167 WP_077696034.1 DUF1524 domain-containing protein -
NIZ24_RS19410 (3991532) 3991532..3992408 - 877 Protein_3788 DUF262 domain-containing protein -
NIZ24_RS19415 (3992633) 3992633..3992806 + 174 Protein_3789 GntR family transcriptional regulator -
NIZ24_RS19420 (3992959) 3992959..3993891 - 933 WP_256878050.1 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12414.23 Da        Isoelectric Point: 7.8219

>T249579 WP_256878049.1 NZ_CP099871:3989924-3990265 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPATEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT249579 NZ_CP099871:c3989929-3989853 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References