249347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3474710..3475409 Replicon chromosome
Accession NZ_CP099727
Organism Pseudomonas putida strain PCL1760

Toxin (Protein)


Gene name mqsR Uniprot ID A0A550F6I7
Locus tag NH673_RS15420 Protein ID WP_019750831.1
Coordinates 3474710..3475006 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7D5VVT2
Locus tag NH673_RS15425 Protein ID WP_029380550.1
Coordinates 3475008..3475409 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH673_RS15400 (NH673_15400) 3470694..3471866 - 1173 WP_076402743.1 efflux RND transporter periplasmic adaptor subunit -
NH673_RS15405 (NH673_15405) 3472093..3472569 + 477 WP_231991505.1 sigma-70 family RNA polymerase sigma factor -
NH673_RS15410 (NH673_15410) 3472738..3473217 + 480 WP_019437855.1 hypothetical protein -
NH673_RS15415 (NH673_15415) 3473290..3474615 + 1326 WP_064493135.1 MFS transporter -
NH673_RS15420 (NH673_15420) 3474710..3475006 + 297 WP_019750831.1 type II toxin-antitoxin system MqsR family toxin Toxin
NH673_RS15425 (NH673_15425) 3475008..3475409 + 402 WP_029380550.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NH673_RS15430 (NH673_15430) 3475485..3477149 - 1665 WP_231991507.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
NH673_RS15435 (NH673_15435) 3477703..3478452 + 750 WP_014590265.1 electron transfer flavoprotein subunit beta/FixA family protein -
NH673_RS15440 (NH673_15440) 3478454..3479395 + 942 WP_004573654.1 FAD-binding protein -
NH673_RS15445 (NH673_15445) 3479471..3480292 + 822 WP_076402746.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11094.88 Da        Isoelectric Point: 9.8759

>T249347 WP_019750831.1 NZ_CP099727:3474710-3475006 [Pseudomonas putida]
MEKRTPHCPLHRLQVLLSQGKVRTTQAATLGARSLGLGPYDMLDVVRGLSPGDFHKSMTSYNDHRIWQDVYRAQTAVGRV
YLKLTVVDDLLILSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14692.91 Da        Isoelectric Point: 4.9749

>AT249347 WP_029380550.1 NZ_CP099727:3475008-3475409 [Pseudomonas putida]
MKCPLCGGAELVAQSRDMPYRYKGEATVIPDIFGDYCPTCGEAVLGMDEAQRMSDLMTAFERKVNAAVVDPGFIAAMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A550F6I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7D5VVT2

References