Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2271487..2272187 Replicon chromosome
Accession NZ_CP099645
Organism Paraburkholderia fungorum strain OTU2SAUBB1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2T1AWY4
Locus tag NHH62_RS12335 Protein ID WP_030100731.1
Coordinates 2271891..2272187 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NHH62_RS12330 Protein ID WP_028197207.1
Coordinates 2271487..2271888 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHH62_RS12320 (NHH62_12325) 2266931..2270413 - 3483 WP_253044792.1 DEAD/DEAH box helicase -
NHH62_RS12325 (NHH62_12330) 2270603..2271382 - 780 WP_028197206.1 DeoR/GlpR family DNA-binding transcription regulator -
NHH62_RS12330 (NHH62_12335) 2271487..2271888 - 402 WP_028197207.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NHH62_RS12335 (NHH62_12340) 2271891..2272187 - 297 WP_030100731.1 type II toxin-antitoxin system MqsR family toxin Toxin
NHH62_RS12340 (NHH62_12345) 2272355..2274859 + 2505 WP_030100732.1 FAD-dependent oxidoreductase -
NHH62_RS12345 (NHH62_12350) 2274826..2275395 - 570 WP_030100733.1 cytochrome b -
NHH62_RS12350 (NHH62_12355) 2275392..2276483 - 1092 WP_030100734.1 catalase family peroxidase -
NHH62_RS12355 (NHH62_12360) 2276591..2276860 - 270 WP_028197212.1 DUF4148 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-48)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10739.53 Da        Isoelectric Point: 7.8545

>T249282 WP_030100731.1 NZ_CP099645:c2272187-2271891 [Paraburkholderia fungorum]
MEKSTPHCKLAEVQSLARAGNIRITKSAVIGAAALGLGPAAIIETLLSLERGNFRKSMTTYADHRVWQDVYCAVTEAGMV
YLKLTVIDDVLVVSFKEW

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14738.86 Da        Isoelectric Point: 5.0016

>AT249282 WP_028197207.1 NZ_CP099645:c2271888-2271487 [Paraburkholderia fungorum]
MKCPNCGAAELVRDTRNMRYVYKGETAVFEAVTGDYCPACDEAVLDIDEATRTGQMMLAFNKEVNASQVDPAFIAAVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTRPPLALIKLLKVLDRHPELLEEVRAS

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T1AWY4

Antitoxin

Source ID Structure

References