Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1987420..1988080 Replicon chromosome
Accession NC_014562
Organism Pantoea vagans C9-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PVAG_RS13335 Protein ID WP_041456964.1
Coordinates 1987727..1988080 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PVAG_RS13330 Protein ID WP_013358385.1
Coordinates 1987420..1987722 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVAG_RS13310 1983260..1984285 - 1026 WP_179291192.1 ABC transporter permease -
PVAG_RS13315 1984309..1985793 - 1485 WP_013358383.1 sugar ABC transporter ATP-binding protein -
PVAG_RS13320 1985826..1986749 - 924 WP_013358384.1 sugar ABC transporter substrate-binding protein -
PVAG_RS13330 1987420..1987722 - 303 WP_013358385.1 XRE family transcriptional regulator Antitoxin
PVAG_RS13335 1987727..1988080 - 354 WP_041456964.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVAG_RS13340 1988340..1988741 - 402 WP_013358387.1 hypothetical protein -
PVAG_RS13345 1988839..1989120 - 282 WP_013358388.1 hypothetical protein -
PVAG_RS13350 1989310..1990611 - 1302 WP_013358389.1 LLM class flavin-dependent oxidoreductase -
PVAG_RS13355 1990657..1991727 - 1071 WP_013358390.1 iron-containing alcohol dehydrogenase family protein -
PVAG_RS13360 1991984..1992529 + 546 WP_013358391.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13602.67 Da        Isoelectric Point: 10.1378

>T24928 WP_041456964.1 NC_014562:c1988080-1987727 [Pantoea vagans C9-1]
VWMIKTTERFDRWFTLLNDSDRACVLAALMVLREKGPGLSRPYADTIKGSAYSNMKELRIQSRGDPIRAFFAFDPNRTAI
VLCAGNKAGNEKRFYREMLPVADREFTHWLKSFNHKE

Download         Length: 354 bp

>T24928 NC_014562:c1988080-1987727 [Pantoea vagans C9-1]
GTGTGGATGATTAAAACGACAGAGCGGTTTGATCGCTGGTTTACGTTGCTTAATGACAGCGATCGCGCCTGCGTGCTGGC
TGCATTGATGGTGCTGCGGGAAAAGGGGCCGGGATTAAGCCGACCCTATGCGGATACGATTAAAGGTTCCGCTTATAGCA
ACATGAAAGAGTTACGTATCCAGAGCCGCGGCGACCCAATAAGGGCTTTCTTTGCTTTTGACCCGAACCGCACGGCAATT
GTGCTGTGTGCCGGTAATAAGGCGGGCAATGAAAAGCGATTTTATCGGGAGATGCTTCCGGTTGCCGATCGGGAATTCAC
ACACTGGCTAAAAAGCTTTAACCATAAGGAGTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10895.70 Da        Isoelectric Point: 5.7134

>AT24928 WP_013358385.1 NC_014562:c1987722-1987420 [Pantoea vagans C9-1]
MGRTLEQLIADEKPEVVADAQAMATEILLNIHLAELREKVQKTQVEMAQALGITQPTVAGMEKPGRDLKLSTLKRYVDAA
GGKLRLVVELPDGSHFGFVV

Download         Length: 303 bp

>AT24928 NC_014562:c1987722-1987420 [Pantoea vagans C9-1]
ATGGGCAGAACGCTGGAACAGCTTATTGCGGATGAAAAACCGGAAGTCGTTGCCGACGCACAGGCTATGGCGACCGAAAT
CCTGCTCAACATTCACCTTGCCGAGCTGCGTGAGAAAGTGCAGAAAACGCAGGTGGAAATGGCGCAGGCGCTGGGCATCA
CACAGCCGACCGTGGCGGGTATGGAAAAGCCGGGGCGTGACCTGAAGCTTTCCACGCTCAAACGCTACGTCGATGCGGCG
GGGGGGAAACTGCGGCTGGTGGTGGAGCTGCCGGATGGTTCCCACTTCGGGTTCGTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References