Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 25057..25757 Replicon chromosome
Accession NZ_CP099629
Organism Paraburkholderia fungorum strain OTU2BAGNBA2

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2T1AWY4
Locus tag NFS19_RS22945 Protein ID WP_030100731.1
Coordinates 25461..25757 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NFS19_RS22940 Protein ID WP_028197207.1
Coordinates 25057..25458 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFS19_RS22930 (NFS19_22920) 20500..23982 - 3483 WP_252890150.1 DEAD/DEAH box helicase -
NFS19_RS22935 (NFS19_22925) 24172..24951 - 780 WP_028197206.1 DeoR/GlpR family DNA-binding transcription regulator -
NFS19_RS22940 (NFS19_22930) 25057..25458 - 402 WP_028197207.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NFS19_RS22945 (NFS19_22935) 25461..25757 - 297 WP_030100731.1 type II toxin-antitoxin system MqsR family toxin Toxin
NFS19_RS22950 (NFS19_22940) 25925..28429 + 2505 WP_046570655.1 FAD-dependent oxidoreductase -
NFS19_RS22955 (NFS19_22945) 28426..28965 - 540 WP_046570668.1 cytochrome b -
NFS19_RS22960 (NFS19_22950) 28962..30053 - 1092 WP_252890149.1 catalase family peroxidase -
NFS19_RS22965 (NFS19_22955) 30161..30430 - 270 WP_028197212.1 DUF4148 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-48)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10739.53 Da        Isoelectric Point: 7.8545

>T249277 WP_030100731.1 NZ_CP099629:c25757-25461 [Paraburkholderia fungorum]
MEKSTPHCKLAEVQSLARAGNIRITKSAVIGAAALGLGPAAIIETLLSLERGNFRKSMTTYADHRVWQDVYCAVTEAGMV
YLKLTVIDDVLVVSFKEW

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14738.86 Da        Isoelectric Point: 5.0016

>AT249277 WP_028197207.1 NZ_CP099629:c25458-25057 [Paraburkholderia fungorum]
MKCPNCGAAELVRDTRNMRYVYKGETAVFEAVTGDYCPACDEAVLDIDEATRTGQMMLAFNKEVNASQVDPAFIAAVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTRPPLALIKLLKVLDRHPELLEEVRAS

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T1AWY4

Antitoxin

Source ID Structure

References