Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4793158..4793813 Replicon chromosome
Accession NZ_CP099602
Organism Pseudomonas siliginis strain OTU6MONTID1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NF680_RS21300 Protein ID WP_252876871.1
Coordinates 4793469..4793813 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF680_RS21295 Protein ID WP_041479944.1
Coordinates 4793158..4793472 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF680_RS21275 (NF680_21275) 4789173..4790345 - 1173 WP_252876869.1 aspartate aminotransferase family protein -
NF680_RS21280 (NF680_21280) 4790448..4791374 + 927 WP_252876870.1 LysR family transcriptional regulator -
NF680_RS21285 (NF680_21285) 4791509..4792210 + 702 WP_016773307.1 hypothetical protein -
NF680_RS21290 (NF680_21290) 4792479..4792970 - 492 WP_016773306.1 RidA family protein -
NF680_RS21295 (NF680_21295) 4793158..4793472 - 315 WP_041479944.1 helix-turn-helix domain-containing protein Antitoxin
NF680_RS21300 (NF680_21300) 4793469..4793813 - 345 WP_252876871.1 toxin Toxin
NF680_RS21305 (NF680_21305) 4793929..4794816 - 888 WP_016773305.1 heme o synthase -
NF680_RS21310 (NF680_21310) 4794827..4795162 - 336 WP_011335842.1 cytochrome o ubiquinol oxidase subunit IV -
NF680_RS21315 (NF680_21315) 4795162..4795785 - 624 WP_016773303.1 cytochrome o ubiquinol oxidase subunit III -
NF680_RS21320 (NF680_21320) 4795789..4797819 - 2031 WP_041479948.1 cytochrome o ubiquinol oxidase subunit I -
NF680_RS21325 (NF680_21325) 4797823..4798764 - 942 WP_024014231.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13553.51 Da        Isoelectric Point: 10.3452

>T249238 WP_252876871.1 NZ_CP099602:c4793813-4793469 [Pseudomonas siliginis]
MRTIFFETTIFTKSVGRYLTDDEYRTLQNYLQSNPLAGDVMPRTGGFRKLRWADSRRSKGRRGGLRVLYYWLMNDGQFWM
FAIYDKDELEKLTAEQERALRTAIDKELKKRGTP

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.82 Da        Isoelectric Point: 9.9443

>AT249238 WP_041479944.1 NZ_CP099602:c4793472-4793158 [Pseudomonas siliginis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFASRIRTSPNTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLNTV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References