Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4794091..4794746 Replicon chromosome
Accession NZ_CP099601
Organism Pseudomonas siliginis strain OTU6MONEA1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NF679_RS21470 Protein ID WP_252868262.1
Coordinates 4794402..4794746 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF679_RS21465 Protein ID WP_041479944.1
Coordinates 4794091..4794405 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF679_RS21440 (NF679_21440) 4789576..4790748 - 1173 WP_252868259.1 aspartate aminotransferase family protein -
NF679_RS21445 (NF679_21445) 4790851..4791771 + 921 WP_252868260.1 LysR family transcriptional regulator -
NF679_RS21450 (NF679_21450) 4791810..4792214 + 405 WP_252868261.1 GNAT family N-acetyltransferase -
NF679_RS21455 (NF679_21455) 4792348..4793049 + 702 WP_016773307.1 hypothetical protein -
NF679_RS21460 (NF679_21460) 4793412..4793903 - 492 WP_016773306.1 RidA family protein -
NF679_RS21465 (NF679_21465) 4794091..4794405 - 315 WP_041479944.1 helix-turn-helix domain-containing protein Antitoxin
NF679_RS21470 (NF679_21470) 4794402..4794746 - 345 WP_252868262.1 toxin Toxin
NF679_RS21475 (NF679_21475) 4794862..4795749 - 888 WP_016773305.1 heme o synthase -
NF679_RS21480 (NF679_21480) 4795760..4796095 - 336 WP_011335842.1 cytochrome o ubiquinol oxidase subunit IV -
NF679_RS21485 (NF679_21485) 4796095..4796718 - 624 WP_024014230.1 cytochrome o ubiquinol oxidase subunit III -
NF679_RS21490 (NF679_21490) 4796722..4798752 - 2031 WP_041479948.1 cytochrome o ubiquinol oxidase subunit I -
NF679_RS21495 (NF679_21495) 4798756..4799697 - 942 WP_024014231.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13611.55 Da        Isoelectric Point: 10.1973

>T249229 WP_252868262.1 NZ_CP099601:c4794746-4794402 [Pseudomonas siliginis]
MRTIFFETTIFTKSVDRYLTDDEYRTLQNYLQSNPLAGDVMPRTGGFRKLRWADSRRSKGRRGGLRVLYYWLMNDGQFWM
FAIYDKDELEKLTAEQERALRTAIDKELKKRGTP

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.82 Da        Isoelectric Point: 9.9443

>AT249229 WP_041479944.1 NZ_CP099601:c4794405-4794091 [Pseudomonas siliginis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFASRIRTSPNTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLNTV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References