249212

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4840174..4840829 Replicon chromosome
Accession NZ_CP099599
Organism Pseudomonas siliginis strain OTU6ESPEB1

Toxin (Protein)


Gene name higB Uniprot ID A0A554AC95
Locus tag NF677_RS21550 Protein ID WP_041479945.1
Coordinates 4840485..4840829 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF677_RS21545 Protein ID WP_041479944.1
Coordinates 4840174..4840488 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF677_RS21525 (NF677_21525) 4836202..4837374 - 1173 WP_252878859.1 aspartate aminotransferase family protein -
NF677_RS21530 (NF677_21530) 4837477..4838403 + 927 WP_236168923.1 LysR family transcriptional regulator -
NF677_RS21535 (NF677_21535) 4838538..4839239 + 702 WP_016773307.1 hypothetical protein -
NF677_RS21540 (NF677_21540) 4839497..4839988 - 492 WP_016773306.1 RidA family protein -
NF677_RS21545 (NF677_21545) 4840174..4840488 - 315 WP_041479944.1 helix-turn-helix domain-containing protein Antitoxin
NF677_RS21550 (NF677_21550) 4840485..4840829 - 345 WP_041479945.1 hypothetical protein Toxin
NF677_RS21555 (NF677_21555) 4840945..4841832 - 888 WP_016773305.1 heme o synthase -
NF677_RS21560 (NF677_21560) 4841843..4842178 - 336 WP_011335842.1 cytochrome o ubiquinol oxidase subunit IV -
NF677_RS21565 (NF677_21565) 4842178..4842801 - 624 WP_016773303.1 cytochrome o ubiquinol oxidase subunit III -
NF677_RS21570 (NF677_21570) 4842805..4844835 - 2031 WP_041479948.1 cytochrome o ubiquinol oxidase subunit I -
NF677_RS21575 (NF677_21575) 4844839..4845780 - 942 WP_024014231.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13523.49 Da        Isoelectric Point: 10.3452

>T249212 WP_041479945.1 NZ_CP099599:c4840829-4840485 [Pseudomonas siliginis]
MRTIFFETTIFTKSVGRYLTDDEYRTLQNYLQSNPLAGDVMPRTGGFRKLRWADSRRGKGRRGGLRVLYYWLMNDGQFWM
FAIYDKDELEKLTAEQERALRTAIDKELKKRGTP

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.82 Da        Isoelectric Point: 9.9443

>AT249212 WP_041479944.1 NZ_CP099599:c4840488-4840174 [Pseudomonas siliginis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFASRIRTSPNTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLNTV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AC95

Antitoxin

Source ID Structure

References