249206

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4830942..4831597 Replicon chromosome
Accession NZ_CP099598
Organism Pseudomonas siliginis strain OTU6BANIB1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NF676_RS22125 Protein ID WP_252886777.1
Coordinates 4831253..4831597 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF676_RS22120 Protein ID WP_041479944.1
Coordinates 4830942..4831256 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF676_RS22100 (NF676_22105) 4826865..4828037 - 1173 WP_252886775.1 aspartate aminotransferase family protein -
NF676_RS22105 (NF676_22110) 4828140..4829066 + 927 WP_252886776.1 LysR family transcriptional regulator -
NF676_RS22110 (NF676_22115) 4829201..4829902 + 702 WP_016773307.1 hypothetical protein -
NF676_RS22115 (NF676_22120) 4830263..4830754 - 492 WP_016773306.1 RidA family protein -
NF676_RS22120 (NF676_22125) 4830942..4831256 - 315 WP_041479944.1 helix-turn-helix domain-containing protein Antitoxin
NF676_RS22125 (NF676_22130) 4831253..4831597 - 345 WP_252886777.1 toxin Toxin
NF676_RS22130 (NF676_22135) 4831713..4832600 - 888 WP_016773305.1 heme o synthase -
NF676_RS22135 (NF676_22140) 4832611..4832946 - 336 WP_011335842.1 cytochrome o ubiquinol oxidase subunit IV -
NF676_RS22140 (NF676_22145) 4832946..4833569 - 624 WP_024014230.1 cytochrome o ubiquinol oxidase subunit III -
NF676_RS22145 (NF676_22150) 4833573..4835603 - 2031 WP_041479948.1 cytochrome o ubiquinol oxidase subunit I -
NF676_RS22150 (NF676_22155) 4835607..4836548 - 942 WP_024014231.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13440.41 Da        Isoelectric Point: 10.2002

>T249206 WP_252886777.1 NZ_CP099598:c4831597-4831253 [Pseudomonas siliginis]
MRTIFFETTIFTKSVGRYLTDDEYRTLQNYLQSNPLAGDVMPRTGGFRKLRWADSRRGKGRRGGLRVLYYCLMNDGQFWM
FAIYDKDELEKLTAEQERALRTAIDKELKKRGTP

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.82 Da        Isoelectric Point: 9.9443

>AT249206 WP_041479944.1 NZ_CP099598:c4831256-4830942 [Pseudomonas siliginis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFASRIRTSPNTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLNTV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References