Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4857411..4858066 Replicon chromosome
Accession NZ_CP099596
Organism Pseudomonas siliginis strain OTU6BAGNBB1

Toxin (Protein)


Gene name higB Uniprot ID A0A554AC95
Locus tag NF675_RS21225 Protein ID WP_041479945.1
Coordinates 4857722..4858066 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF675_RS21220 Protein ID WP_041479944.1
Coordinates 4857411..4857725 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF675_RS21200 (NF675_21200) 4853438..4854610 - 1173 WP_252878859.1 aspartate aminotransferase family protein -
NF675_RS21205 (NF675_21205) 4854713..4855639 + 927 WP_252878860.1 LysR family transcriptional regulator -
NF675_RS21210 (NF675_21210) 4855774..4856475 + 702 WP_016773307.1 hypothetical protein -
NF675_RS21215 (NF675_21215) 4856734..4857225 - 492 WP_016773306.1 RidA family protein -
NF675_RS21220 (NF675_21220) 4857411..4857725 - 315 WP_041479944.1 helix-turn-helix domain-containing protein Antitoxin
NF675_RS21225 (NF675_21225) 4857722..4858066 - 345 WP_041479945.1 hypothetical protein Toxin
NF675_RS21230 (NF675_21230) 4858182..4859069 - 888 WP_016773305.1 heme o synthase -
NF675_RS21235 (NF675_21235) 4859080..4859415 - 336 WP_011335842.1 cytochrome o ubiquinol oxidase subunit IV -
NF675_RS21240 (NF675_21240) 4859415..4860038 - 624 WP_024014230.1 cytochrome o ubiquinol oxidase subunit III -
NF675_RS21245 (NF675_21245) 4860042..4862072 - 2031 WP_041479948.1 cytochrome o ubiquinol oxidase subunit I -
NF675_RS21250 (NF675_21250) 4862076..4863017 - 942 WP_024014231.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13523.49 Da        Isoelectric Point: 10.3452

>T249197 WP_041479945.1 NZ_CP099596:c4858066-4857722 [Pseudomonas siliginis]
MRTIFFETTIFTKSVGRYLTDDEYRTLQNYLQSNPLAGDVMPRTGGFRKLRWADSRRGKGRRGGLRVLYYWLMNDGQFWM
FAIYDKDELEKLTAEQERALRTAIDKELKKRGTP

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.82 Da        Isoelectric Point: 9.9443

>AT249197 WP_041479944.1 NZ_CP099596:c4857725-4857411 [Pseudomonas siliginis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFASRIRTSPNTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLNTV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AC95

Antitoxin

Source ID Structure

References