Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1934933..1935115 Replicon chromosome
Accession NZ_CP099576
Organism Staphylococcus aureus strain MRSA1369

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag NHB12_RS09425 Protein ID WP_001801861.1
Coordinates 1934933..1935028 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1935056..1935115 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHB12_RS09385 1930593..1931219 + 627 Protein_1847 hypothetical protein -
NHB12_RS09390 1931260..1931604 + 345 WP_000627551.1 DUF3969 family protein -
NHB12_RS09395 1931702..1932253 + 552 WP_000414205.1 hypothetical protein -
NHB12_RS09400 1932471..1933112 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
NHB12_RS09405 1933226..1933411 - 186 WP_000809857.1 hypothetical protein -
NHB12_RS09410 1933413..1933589 - 177 WP_000375476.1 hypothetical protein -
NHB12_RS09415 1933600..1933983 - 384 WP_000070811.1 hypothetical protein -
NHB12_RS09420 1934587..1934730 - 144 WP_001549059.1 transposase -
NHB12_RS09425 1934933..1935028 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1935056..1935115 - 60 - - Antitoxin
NHB12_RS09430 1935151..1935252 + 102 WP_001791893.1 hypothetical protein -
NHB12_RS09435 1935230..1935406 - 177 Protein_1857 transposase -
NHB12_RS09440 1935600..1935977 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T249116 WP_001801861.1 NZ_CP099576:1934933-1935028 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT249116 NZ_CP099576:c1935115-1935056 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References