Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 755407..755917 Replicon chromosome
Accession NZ_CP099544
Organism Photobacterium damselae strain XP-11

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2T3QIJ8
Locus tag NGM67_RS03090 Protein ID WP_036765839.1
Coordinates 755657..755917 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T3QIT0
Locus tag NGM67_RS03085 Protein ID WP_036765838.1
Coordinates 755407..755667 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGM67_RS03060 (NGM67_03060) 750948..751703 + 756 WP_151182533.1 TPM domain-containing protein -
NGM67_RS03065 (NGM67_03065) 751706..752323 + 618 WP_106142426.1 TPM domain-containing protein -
NGM67_RS03070 (NGM67_03070) 752498..752716 + 219 WP_050787827.1 YgjV family protein -
NGM67_RS03075 (NGM67_03075) 752723..753457 + 735 WP_005305885.1 hypothetical protein -
NGM67_RS03080 (NGM67_03080) 753532..755214 + 1683 WP_106142453.1 RluA family pseudouridine synthase -
NGM67_RS03085 (NGM67_03085) 755407..755667 + 261 WP_036765838.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NGM67_RS03090 (NGM67_03090) 755657..755917 + 261 WP_036765839.1 Txe/YoeB family addiction module toxin Toxin
NGM67_RS03095 (NGM67_03095) 755975..756229 - 255 WP_069532913.1 hypothetical protein -
NGM67_RS03100 (NGM67_03100) 756241..757125 - 885 WP_065171313.1 AraC family transcriptional regulator -
NGM67_RS03105 (NGM67_03105) 757285..758433 + 1149 WP_086368441.1 iron-containing alcohol dehydrogenase -
NGM67_RS03110 (NGM67_03110) 758618..759454 + 837 WP_252689155.1 HNH endonuclease signature motif containing protein -
NGM67_RS03115 (NGM67_03115) 759516..760418 - 903 WP_068946067.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10319.86 Da        Isoelectric Point: 9.7118

>T249105 WP_036765839.1 NZ_CP099544:755657-755917 [Photobacterium damselae]
MMINFTPNAWDDYLYWQSQDKKTLKRINKLIENCVRTPFEGIGKPEPLKDNLSGYWSRRIDDTHRLVYKATQDTLVIVAV
RFHYQK

Download         Length: 261 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9718.89 Da        Isoelectric Point: 4.3167

>AT249105 WP_036765838.1 NZ_CP099544:755407-755667 [Photobacterium damselae]
MTVLSFSEVRGNFKKVCDQVVDDCDAVVIHRRDADNVVLMSESEFNSWKETMYLMSNPVNAANLLESIKQAECGNVQTHE
LLSHDD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T3QIJ8

Antitoxin

Source ID Structure
AlphaFold DB A0A2T3QIT0

References