Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 142711..143299 Replicon chromosome
Accession NZ_CP099534
Organism Xanthomonas sacchari strain JR3-14

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NG824_RS00645 Protein ID WP_267093239.1
Coordinates 142711..142992 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NG824_RS00650 Protein ID WP_267093240.1
Coordinates 143009..143299 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG824_RS00630 (NG824_00630) 138992..140983 + 1992 WP_267093237.1 exodeoxyribonuclease V subunit alpha -
NG824_RS00635 (NG824_00635) 141083..142063 + 981 WP_267093238.1 virulence RhuM family protein -
NG824_RS00640 (NG824_00640) 142165..142497 - 333 WP_010341478.1 hypothetical protein -
NG824_RS00645 (NG824_00645) 142711..142992 + 282 WP_267093239.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NG824_RS00650 (NG824_00650) 143009..143299 + 291 WP_267093240.1 HigA family addiction module antitoxin Antitoxin
NG824_RS00655 (NG824_00655) 143456..144589 - 1134 WP_267093241.1 hypothetical protein -
NG824_RS00660 (NG824_00660) 144852..145676 - 825 WP_267093242.1 restriction endonuclease -
NG824_RS00665 (NG824_00665) 145948..146649 + 702 WP_267093243.1 DUF2306 domain-containing protein -
NG824_RS00670 (NG824_00670) 146952..148214 - 1263 WP_267093244.1 lipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-67)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.52 Da        Isoelectric Point: 10.7629

>T249085 WP_267093239.1 NZ_CP099534:142711-142992 [Xanthomonas sacchari]
VIRSFIDKEAEKIWRGERSRRLPADIQPVARRKLRMLNAAAGLEDLRVPPANRLEALKGDRRGQHSIRINDQWRICFRWH
EGDVAEVAIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10492.14 Da        Isoelectric Point: 8.7925

>AT249085 WP_267093240.1 NZ_CP099534:143009-143299 [Xanthomonas sacchari]
MASLPNIHPGEVLRDEFLVPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTTERFWLSLQADYELEEA
HRLLGDLPARIRRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References