Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2265861..2266045 Replicon chromosome
Accession NZ_CP099508
Organism Staphylococcus aureus strain S82

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LPT18_RS10945 Protein ID WP_000482647.1
Coordinates 2265861..2265968 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2265985..2266045 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT18_RS10920 2261218..2261691 + 474 WP_000456489.1 GyrI-like domain-containing protein -
LPT18_RS10925 2261814..2263025 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
LPT18_RS10930 2263213..2263872 - 660 WP_000831300.1 hypothetical protein -
LPT18_RS10935 2263932..2265074 - 1143 WP_001176859.1 glycerate kinase -
LPT18_RS10940 2265341..2265727 + 387 WP_000779355.1 flippase GtxA -
LPT18_RS10945 2265861..2265968 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2265985..2266045 - 61 - - Antitoxin
LPT18_RS10950 2266672..2268435 + 1764 WP_001064818.1 ABC transporter ATP-binding protein -
LPT18_RS10955 2268460..2270193 + 1734 Protein_2124 ABC transporter ATP-binding protein -
LPT18_RS10960 2270424..2270591 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T249028 WP_000482647.1 NZ_CP099508:2265861-2265968 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT249028 NZ_CP099508:c2266045-2265985 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References