Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2108006..2108190 Replicon chromosome
Accession NZ_CP099506
Organism Staphylococcus aureus strain 0316-H-5A

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LPT22_RS10620 Protein ID WP_000482647.1
Coordinates 2108083..2108190 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2108006..2108066 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT22_RS10605 2103460..2103627 - 168 WP_001798790.1 hypothetical protein -
LPT22_RS10610 2103858..2105591 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
LPT22_RS10615 2105616..2107379 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2108006..2108066 + 61 - - Antitoxin
LPT22_RS10620 2108083..2108190 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
LPT22_RS10625 2108324..2108710 - 387 WP_000779355.1 flippase GtxA -
LPT22_RS10630 2108977..2110119 + 1143 WP_001176859.1 glycerate kinase -
LPT22_RS10635 2110179..2110838 + 660 WP_000831300.1 hypothetical protein -
LPT22_RS10640 2111026..2112237 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
LPT22_RS10645 2112360..2112833 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T249019 WP_000482647.1 NZ_CP099506:c2108190-2108083 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT249019 NZ_CP099506:2108006-2108066 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References