Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 1812267..1812465 Replicon chromosome
Accession NZ_CP099506
Organism Staphylococcus aureus strain 0316-H-5A

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LPT22_RS09075 Protein ID WP_001802298.1
Coordinates 1812361..1812465 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1812267..1812305 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT22_RS09050 1808387..1809052 - 666 WP_001024099.1 SDR family oxidoreductase -
LPT22_RS09055 1809204..1809524 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPT22_RS09060 1809526..1810506 + 981 WP_031886446.1 CDF family zinc efflux transporter CzrB -
LPT22_RS09065 1810772..1811863 + 1092 WP_000495673.1 hypothetical protein -
LPT22_RS09070 1812247..1812321 + 75 Protein_1747 hypothetical protein -
- 1812267..1812305 + 39 - - Antitoxin
LPT22_RS09075 1812361..1812465 - 105 WP_001802298.1 hypothetical protein Toxin
LPT22_RS09080 1813145..1813303 + 159 WP_001792784.1 hypothetical protein -
LPT22_RS09085 1813961..1814818 - 858 WP_000370942.1 HAD family hydrolase -
LPT22_RS09090 1814886..1815668 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
LPT22_RS09095 1815958..1816566 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T249018 WP_001802298.1 NZ_CP099506:c1812465-1812361 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT249018 NZ_CP099506:1812267-1812305 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References