Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2209396..2209659 Replicon chromosome
Accession NZ_CP099504
Organism Staphylococcus aureus strain S36

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LPT20_RS10600 Protein ID WP_001802298.1
Coordinates 2209396..2209500 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2209495..2209659 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT20_RS10570 (LPT20_10570) 2204790..2205572 + 783 WP_000908190.1 ABC transporter ATP-binding protein -
LPT20_RS10575 (LPT20_10575) 2205640..2206497 + 858 WP_000370919.1 HAD family hydrolase -
LPT20_RS10585 (LPT20_10585) 2207192..2207284 - 93 WP_031844941.1 hypothetical protein -
LPT20_RS10590 (LPT20_10590) 2207573..2208709 + 1137 Protein_2084 SAP domain-containing protein -
LPT20_RS10595 (LPT20_10595) 2208752..2209235 + 484 Protein_2085 recombinase family protein -
LPT20_RS10600 (LPT20_10600) 2209396..2209500 + 105 WP_001802298.1 hypothetical protein Toxin
- 2209495..2209659 - 165 - - Antitoxin
LPT20_RS10610 (LPT20_10610) 2209949..2211040 - 1092 WP_000495695.1 hypothetical protein -
LPT20_RS10615 (LPT20_10615) 2211306..2212283 - 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
LPT20_RS10620 (LPT20_10620) 2212285..2212605 - 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPT20_RS10625 (LPT20_10625) 2212757..2213422 + 666 WP_001024088.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T249002 WP_001802298.1 NZ_CP099504:2209396-2209500 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT249002 NZ_CP099504:c2209659-2209495 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References