Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1922690..1922874 Replicon chromosome
Accession NZ_CP099504
Organism Staphylococcus aureus strain S36

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LPT20_RS09110 Protein ID WP_000482647.1
Coordinates 1922690..1922797 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1922814..1922874 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT20_RS09085 (LPT20_09085) 1918052..1918525 + 474 WP_000456483.1 GyrI-like domain-containing protein -
LPT20_RS09090 (LPT20_09090) 1918648..1919859 - 1212 WP_001191921.1 multidrug effflux MFS transporter -
LPT20_RS09095 (LPT20_09095) 1920042..1920701 - 660 WP_000831298.1 membrane protein -
LPT20_RS09100 (LPT20_09100) 1920761..1921903 - 1143 WP_001176863.1 glycerate kinase -
LPT20_RS09105 (LPT20_09105) 1922171..1922557 + 387 WP_000779353.1 flippase GtxA -
LPT20_RS09110 (LPT20_09110) 1922690..1922797 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1922814..1922874 - 61 - - Antitoxin
LPT20_RS09115 (LPT20_09115) 1922824..1922991 + 168 WP_000301893.1 hypothetical protein -
LPT20_RS09120 (LPT20_09120) 1923445..1925157 + 1713 WP_001064821.1 ABC transporter ATP-binding protein -
LPT20_RS09125 (LPT20_09125) 1925233..1926966 + 1734 WP_000488493.1 ABC transporter ATP-binding protein -
LPT20_RS09130 (LPT20_09130) 1927197..1927364 + 168 WP_031845053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T249000 WP_000482647.1 NZ_CP099504:1922690-1922797 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT249000 NZ_CP099504:c1922874-1922814 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References