Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2535946..2536209 Replicon chromosome
Accession NZ_CP099502
Organism Staphylococcus aureus strain JL42

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LPT17_RS12390 Protein ID WP_001802298.1
Coordinates 2535946..2536050 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2536045..2536209 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT17_RS12365 2531845..2532453 + 609 WP_000101714.1 TIR domain-containing protein -
LPT17_RS12370 2532743..2533525 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
LPT17_RS12375 2533593..2534450 + 858 WP_000370942.1 HAD family hydrolase -
LPT17_RS12380 2534580..2534672 - 93 WP_000220902.1 hypothetical protein -
LPT17_RS12385 2535108..2535266 - 159 WP_001792784.1 hypothetical protein -
LPT17_RS12390 2535946..2536050 + 105 WP_001802298.1 hypothetical protein Toxin
- 2536045..2536209 - 165 - - Antitoxin
LPT17_RS12400 2536548..2537639 - 1092 WP_000495673.1 hypothetical protein -
LPT17_RS12405 2537905..2538885 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
LPT17_RS12410 2538887..2539207 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPT17_RS12415 2539359..2540024 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T248992 WP_001802298.1 NZ_CP099502:2535946-2536050 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT248992 NZ_CP099502:c2536209-2536045 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References