Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2064518..2064702 Replicon chromosome
Accession NZ_CP099499
Organism Staphylococcus aureus strain 0610-H-2A

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LPT19_RS10280 Protein ID WP_000482647.1
Coordinates 2064595..2064702 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2064518..2064578 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT19_RS10265 (LPT19_10265) 2059972..2060139 - 168 WP_001798790.1 hypothetical protein -
LPT19_RS10270 (LPT19_10270) 2060370..2062103 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
LPT19_RS10275 (LPT19_10275) 2062128..2063891 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2064518..2064578 + 61 - - Antitoxin
LPT19_RS10280 (LPT19_10280) 2064595..2064702 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
LPT19_RS10285 (LPT19_10285) 2064836..2065222 - 387 WP_000779355.1 flippase GtxA -
LPT19_RS10290 (LPT19_10290) 2065489..2066631 + 1143 WP_001176859.1 glycerate kinase -
LPT19_RS10295 (LPT19_10295) 2066691..2067350 + 660 WP_000831300.1 hypothetical protein -
LPT19_RS10300 (LPT19_10300) 2067538..2068749 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
LPT19_RS10305 (LPT19_10305) 2068872..2069345 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T248982 WP_000482647.1 NZ_CP099499:c2064702-2064595 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT248982 NZ_CP099499:2064518-2064578 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References