Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2070561..2070745 Replicon chromosome
Accession NZ_CP099497
Organism Staphylococcus aureus strain 0213-M-4A

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LPT21_RS10290 Protein ID WP_000482647.1
Coordinates 2070638..2070745 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2070561..2070621 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT21_RS10275 (LPT21_10275) 2066015..2066182 - 168 WP_001798790.1 hypothetical protein -
LPT21_RS10280 (LPT21_10280) 2066413..2068146 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
LPT21_RS10285 (LPT21_10285) 2068171..2069934 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2070561..2070621 + 61 - - Antitoxin
LPT21_RS10290 (LPT21_10290) 2070638..2070745 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
LPT21_RS10295 (LPT21_10295) 2070879..2071265 - 387 WP_000779355.1 flippase GtxA -
LPT21_RS10300 (LPT21_10300) 2071532..2072674 + 1143 WP_001176859.1 glycerate kinase -
LPT21_RS10305 (LPT21_10305) 2072734..2073393 + 660 WP_000831300.1 hypothetical protein -
LPT21_RS10310 (LPT21_10310) 2073581..2074792 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
LPT21_RS10315 (LPT21_10315) 2074915..2075388 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T248973 WP_000482647.1 NZ_CP099497:c2070745-2070638 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT248973 NZ_CP099497:2070561-2070621 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References