Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 1774892..1775090 Replicon chromosome
Accession NZ_CP099497
Organism Staphylococcus aureus strain 0213-M-4A

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LPT21_RS08735 Protein ID WP_001802298.1
Coordinates 1774986..1775090 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1774892..1774930 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT21_RS08710 (LPT21_08710) 1771012..1771677 - 666 WP_001024099.1 SDR family oxidoreductase -
LPT21_RS08715 (LPT21_08715) 1771829..1772149 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPT21_RS08720 (LPT21_08720) 1772151..1773131 + 981 WP_031886446.1 CDF family zinc efflux transporter CzrB -
LPT21_RS08725 (LPT21_08725) 1773397..1774488 + 1092 WP_000495673.1 hypothetical protein -
LPT21_RS08730 (LPT21_08730) 1774872..1774946 + 75 Protein_1677 hypothetical protein -
- 1774892..1774930 + 39 - - Antitoxin
LPT21_RS08735 (LPT21_08735) 1774986..1775090 - 105 WP_001802298.1 hypothetical protein Toxin
LPT21_RS08740 (LPT21_08740) 1775770..1775928 + 159 WP_083320583.1 integrase -
LPT21_RS08745 (LPT21_08745) 1776364..1776456 + 93 WP_000220902.1 hypothetical protein -
LPT21_RS08750 (LPT21_08750) 1776586..1777443 - 858 WP_229360409.1 HAD family hydrolase -
LPT21_RS08755 (LPT21_08755) 1777511..1778293 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
LPT21_RS08760 (LPT21_08760) 1778583..1779191 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T248972 WP_001802298.1 NZ_CP099497:c1775090-1774986 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT248972 NZ_CP099497:1774892-1774930 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References