248963

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2559901..2560164 Replicon chromosome
Accession NZ_CP099495
Organism Staphylococcus aureus strain JL28

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LPT16_RS12495 Protein ID WP_001802298.1
Coordinates 2559901..2560005 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2560000..2560164 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT16_RS12470 2555800..2556408 + 609 WP_000101714.1 TIR domain-containing protein -
LPT16_RS12475 2556698..2557480 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
LPT16_RS12480 2557548..2558405 + 858 WP_000370942.1 HAD family hydrolase -
LPT16_RS12485 2558535..2558627 - 93 WP_000220902.1 hypothetical protein -
LPT16_RS12490 2559063..2559221 - 159 WP_001792784.1 hypothetical protein -
LPT16_RS12495 2559901..2560005 + 105 WP_001802298.1 hypothetical protein Toxin
- 2560000..2560164 - 165 - - Antitoxin
LPT16_RS12505 2560503..2561594 - 1092 WP_000495673.1 hypothetical protein -
LPT16_RS12510 2561860..2562840 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
LPT16_RS12515 2562842..2563162 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPT16_RS12520 2563314..2563979 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T248963 WP_001802298.1 NZ_CP099495:2559901-2560005 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT248963 NZ_CP099495:c2560164-2560000 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References