Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 496751..497282 Replicon chromosome
Accession NZ_CP099481
Organism Companilactobacillus allii strain WiKim39

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag M5C72_RS02375 Protein ID WP_076614513.1
Coordinates 496998..497282 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag M5C72_RS02370 Protein ID WP_076614512.1
Coordinates 496751..497005 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5C72_RS02350 (M5C72_02350) 492184..493470 + 1287 WP_225972244.1 Fe-S cluster assembly protein SufD -
M5C72_RS02355 (M5C72_02355) 493457..494674 + 1218 WP_076614509.1 cysteine desulfurase -
M5C72_RS02360 (M5C72_02360) 494661..495098 + 438 WP_076614510.1 SUF system NifU family Fe-S cluster assembly protein -
M5C72_RS02365 (M5C72_02365) 495112..496554 + 1443 WP_076614511.1 Fe-S cluster assembly protein SufB -
M5C72_RS02370 (M5C72_02370) 496751..497005 + 255 WP_076614512.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M5C72_RS02375 (M5C72_02375) 496998..497282 + 285 WP_076614513.1 type II toxin-antitoxin system YafQ family toxin Toxin
M5C72_RS02380 (M5C72_02380) 497506..499842 - 2337 WP_076614514.1 HAD-IC family P-type ATPase -
M5C72_RS02385 (M5C72_02385) 499922..500584 + 663 WP_076614515.1 HAD hydrolase-like protein -
M5C72_RS02390 (M5C72_02390) 500591..501409 + 819 WP_076614516.1 hypothetical protein -
M5C72_RS02395 (M5C72_02395) 501425..501790 + 366 WP_076614517.1 iron-sulfur cluster biosynthesis family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-82)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11052.17 Da        Isoelectric Point: 10.6282

>T248937 WP_076614513.1 NZ_CP099481:496998-497282 [Companilactobacillus allii]
MLEIVQTPTFVKDFKKLKKKHYNMLLLKKVVTHIVKGENEILVSKYRDHALKGNWQGFREVHIEKDWLLVYLVNKGELRL
ALIRTGSHSQILGK

Download         Length: 285 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9779.07 Da        Isoelectric Point: 4.6722

>AT248937 WP_076614512.1 NZ_CP099481:496751-497005 [Companilactobacillus allii]
MSDTRISLRIDPELKKDAQELYSDLGLDLTSAVTMFLKQSVREQALPFKPELEDSESVQARKEAFKKDLKKYKTVDDWWD
NLNA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References