248921

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-Phd
Location 2892094..2892590 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NG743_RS13130 Protein ID WP_027403216.1
Coordinates 2892094..2892357 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0K2M4E0
Locus tag NG743_RS13135 Protein ID WP_027403217.1
Coordinates 2892354..2892590 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS13110 (NG743_13035) 2888415..2889089 + 675 WP_027403212.1 Mo-dependent nitrogenase C-terminal domain-containing protein -
NG743_RS13115 (NG743_13040) 2889142..2889516 + 375 WP_027403213.1 four helix bundle protein -
NG743_RS13120 (NG743_13045) 2889559..2890599 + 1041 WP_193962778.1 GTPase ObgE -
NG743_RS13125 (NG743_13050) 2890775..2891539 - 765 WP_027403215.1 RNA methyltransferase -
NG743_RS13130 (NG743_13055) 2892094..2892357 - 264 WP_027403216.1 Txe/YoeB family addiction module toxin Toxin
NG743_RS13135 (NG743_13060) 2892354..2892590 - 237 WP_027403217.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NG743_RS13140 (NG743_13065) 2892887..2893237 + 351 WP_027403218.1 translation initiation factor -
NG743_RS13145 (NG743_13070) 2893332..2893493 + 162 WP_035082904.1 YqaE/Pmp3 family membrane protein -
NG743_RS13150 (NG743_13075) 2893576..2894214 + 639 WP_027403219.1 DUF1295 domain-containing protein -
NG743_RS13155 (NG743_13080) 2894394..2894777 + 384 WP_027403220.1 hypothetical protein -
NG743_RS13160 (NG743_13085) 2895013..2897577 - 2565 WP_027403221.1 alpha-glucan family phosphorylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10267.83 Da        Isoelectric Point: 9.6969

>T248921 WP_027403216.1 NZ_CP099464:c2892357-2892094 [Dolichospermum heterosporum TAC447]
VNWNLVYTKQAQKDAKKLAVSNLKDKAQILLNIIQINPFQNPPQYEKLVGDLEGAYSRRINIQHRLVYEVIESENTVKVL
RMWTHYE

Download         Length: 264 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8666.70 Da        Isoelectric Point: 3.8428

>AT248921 WP_027403217.1 NZ_CP099464:c2892590-2892354 [Dolichospermum heterosporum TAC447]
MISINQAQQQLQNLIDSVNQSHQPIVISGDNSNAVLLSEADWKSIQETLYLLSIPGMRESIKEGLATPIEECNGELDW

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2M4E0

References