Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 3044594..3045243 Replicon chromosome
Accession NZ_CP099397
Organism Pseudomonas hydrolytica strain DSWY01

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag L1F06_RS14080 Protein ID WP_047588122.1
Coordinates 3044594..3044938 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8I0SEX5
Locus tag L1F06_RS14085 Protein ID WP_003116648.1
Coordinates 3044935..3045243 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1F06_RS14065 (L1F06_014065) 3040357..3042210 + 1854 WP_014596887.1 asparagine synthase (glutamine-hydrolyzing) -
L1F06_RS14070 (L1F06_014070) 3042297..3043496 + 1200 WP_074915921.1 MFS transporter -
L1F06_RS14075 (L1F06_014075) 3043510..3044436 + 927 WP_129482275.1 LysR family transcriptional regulator -
L1F06_RS14080 (L1F06_014080) 3044594..3044938 + 345 WP_047588122.1 toxin Toxin
L1F06_RS14085 (L1F06_014085) 3044935..3045243 + 309 WP_003116648.1 transcriptional regulator Antitoxin
L1F06_RS14090 (L1F06_014090) 3045630..3046499 - 870 WP_003116646.1 LysR family transcriptional regulator -
L1F06_RS14095 (L1F06_014095) 3047133..3048284 - 1152 WP_129482274.1 trypsin-like peptidase domain-containing protein -
L1F06_RS14100 (L1F06_014100) 3048304..3049266 - 963 WP_003116644.1 zinc metalloprotease HtpX -
L1F06_RS14105 (L1F06_014105) 3049253..3049741 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
L1F06_RS14110 (L1F06_014110) 3049783..3050001 - 219 WP_043942199.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-92)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13366.33 Da        Isoelectric Point: 10.2892

>T248874 WP_047588122.1 NZ_CP099397:3044594-3044938 [Pseudomonas hydrolytica]
MKALFVELSPFERNRKAHLDDDEYSLFQQMLLTNPEAGAVIANSGGLRKVRFGSVRRNKGKRGGVRVIYYYWLRGLQFWL
FTLYDKDELDDLSSDQRRQLKALLEREVKARQAP

Download         Length: 345 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11604.36 Da        Isoelectric Point: 10.0927

>AT248874 WP_003116648.1 NZ_CP099397:3044935-3045243 [Pseudomonas hydrolytica]
MTKRDIFSELIEGFDDLASAREGKRTLRTHKVEYKPIEPATGAEIVALREKLQMSQGVFAQAIHAKPATLKNWEQNRSKP
NDQATVLIRILNKHPDLIRELA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References