Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 784281..784908 Replicon chromosome
Accession NC_014394
Organism Gallionella capsiferriformans ES-2

Toxin (Protein)


Gene name higB Uniprot ID D9SDM2
Locus tag GALF_RS03725 Protein ID WP_013292720.1
Coordinates 784281..784610 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GALF_RS03730 Protein ID WP_013292721.1
Coordinates 784600..784908 (+) Length 103 a.a.

Genomic Context

GALF_RS03695GALF_RS03700GALF_RS03705GALF_RS03715GALF_RS03725GALF_RS03730GALF_RS03735GALF_RS03740GALF_RS03750GALF_RS03755GALF_RS03760GALF_RS03765GALF_RS14790GALF_RS03710GALF_RS03720
Location: 781246..781506 (261 bp)
Type: Others
Protein ID: WP_013292713.1
Location: 781506..781781 (276 bp)
Type: Others
Protein ID: WP_013292714.1
Location: 781844..782065 (222 bp)
Type: Others
Protein ID: WP_013292715.1
Location: 783008..783475 (468 bp)
Type: Others
Protein ID: WP_013292717.1
Location: 784281..784610 (330 bp)
Type: Toxin
Protein ID: WP_013292720.1
Location: 784600..784908 (309 bp)
Type: Antitoxin
Protein ID: WP_013292721.1
Location: 785300..786301 (1002 bp)
Type: Others
Protein ID: WP_013292722.1
Location: 786345..786644 (300 bp)
Type: Others
Protein ID: WP_013292723.1
Location: 786817..787098 (282 bp)
Type: Others
Protein ID: Protein_728
Location: 787119..787559 (441 bp)
Type: Others
Protein ID: WP_013292724.1
Location: 787619..788026 (408 bp)
Type: Others
Protein ID: WP_013292725.1
Location: 788402..788665 (264 bp)
Type: Others
Protein ID: WP_013292726.1
Location: 779526..780866 (1341 bp)
Type: Others
Protein ID: WP_013292712.1
Location: 782215..782886 (672 bp)
Type: Others
Protein ID: WP_013292716.1
Location: 783753..783980 (228 bp)
Type: Others
Protein ID: WP_013292718.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GALF_RS14790779526..780866-1341WP_013292712.1integrase family protein-
GALF_RS03695781246..781506+261WP_013292713.1ribbon-helix-helix domain-containing protein-
GALF_RS03700781506..781781+276WP_013292714.1type II toxin-antitoxin system RelE/ParE family toxin-
GALF_RS03705781844..782065+222WP_013292715.1RNA-binding S4 domain-containing protein-
GALF_RS03710782215..782886-672WP_013292716.1Crp/Fnr family transcriptional regulator-
GALF_RS03715783008..783475+468WP_013292717.1cytochrome c-
GALF_RS03720783753..783980-228WP_013292718.1hypothetical protein-
GALF_RS03725784281..784610+330WP_013292720.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GALF_RS03730784600..784908+309WP_013292721.1helix-turn-helix domain-containing proteinAntitoxin
GALF_RS03735785300..786301+1002WP_013292722.1NERD domain-containing protein-
GALF_RS03740786345..786644+300WP_013292723.1GIY-YIG nuclease family protein-
GALF_RS03750786817..787098+282Protein_728integration host factor subunit beta-
GALF_RS03755787119..787559+441WP_013292724.1hypothetical protein-
GALF_RS03760787619..788026+408WP_013292725.1hypothetical protein-
GALF_RS03765788402..788665+264WP_013292726.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--714838..78509870260


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-97)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12495.60 Da        Isoelectric Point: 10.3872

>T24873 WP_013292720.1 NC_014394:784281-784610 [Gallionella capsiferriformans ES-2]
MNWRIIYFSERVRSDVLALPPGIRADYLRLAELMEEHGADLRMPHSKAMGSGLFELRPKGPEGIGRVFYCTQVGQMIVVL
HSFVKKTQRTPNNELDIATRRLKEVKNAK

Download         Length: 330 bp

>T24873 NC_014394:784281-784610 [Gallionella capsiferriformans ES-2]
ATGAACTGGCGGATAATTTACTTTTCTGAACGTGTGCGATCTGATGTGTTGGCCTTGCCTCCCGGCATCCGAGCCGACTA
TCTGCGTCTGGCTGAACTGATGGAAGAACATGGTGCCGACTTGAGGATGCCTCACTCCAAGGCAATGGGAAGTGGTCTGT
TTGAATTACGTCCCAAAGGCCCGGAGGGAATCGGTCGTGTGTTCTACTGTACTCAGGTAGGGCAGATGATTGTTGTGCTT
CATTCATTCGTCAAGAAGACACAAAGAACACCGAATAATGAGTTGGATATTGCGACCCGTCGCTTGAAGGAGGTTAAAAA
TGCAAAATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11347.82 Da        Isoelectric Point: 6.9780

>AT24873 WP_013292721.1 NC_014394:784600-784908 [Gallionella capsiferriformans ES-2]
MQNERFNPVAHDDAFVAQMLSDVETKHAYDELEEEYVALHAVLRARREAGLTQSEIAQRMGTTTSAVSRLESSLISQKHS
PSFSTLKKYAHACGKKLVISLA

Download         Length: 309 bp

>AT24873 NC_014394:784600-784908 [Gallionella capsiferriformans ES-2]
ATGCAAAATGAACGATTCAATCCTGTTGCTCACGATGATGCGTTTGTTGCTCAGATGTTGAGTGATGTTGAAACAAAACA
TGCCTATGATGAGCTTGAGGAAGAGTATGTGGCTCTGCATGCTGTCTTGCGTGCTCGTCGTGAGGCTGGCTTGACACAGT
CCGAGATTGCTCAACGCATGGGTACAACAACTAGTGCAGTGTCTCGTCTGGAGTCATCTCTGATCAGTCAGAAGCATTCG
CCTAGTTTTTCGACATTGAAAAAATATGCTCATGCTTGCGGGAAAAAATTGGTGATCAGTCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBD9SDM2

Antitoxin

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Source
ID
Structure
No matching records found

References