Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 9783..10284 Replicon plasmid unnamed2
Accession NZ_CP099346
Organism Escherichia marmotae strain RHB35-E2-C08

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NFK54_RS24260 Protein ID WP_279283701.1
Coordinates 10009..10284 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NFK54_RS24255 Protein ID WP_279283700.1
Coordinates 9783..10028 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK54_RS24230 (6543) 6543..7034 + 492 WP_279283707.1 type IV secretion protein Rhs -
NFK54_RS24235 (7031) 7031..7423 + 393 WP_279283697.1 hypothetical protein -
NFK54_RS24240 (7436) 7436..7969 + 534 WP_107136013.1 type VI secretion system tube protein TssD -
NFK54_RS24245 (9046) 9046..9282 - 237 WP_279283698.1 protein L -
NFK54_RS24250 (9301) 9301..9561 - 261 WP_279283699.1 hypothetical protein -
NFK54_RS24255 (9783) 9783..10028 + 246 WP_279283700.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NFK54_RS24260 (10009) 10009..10284 + 276 WP_279283701.1 Txe/YoeB family addiction module toxin Toxin
NFK54_RS24265 (10509) 10509..11078 + 570 Protein_10 replication initiation protein -
NFK54_RS24270 (11231) 11231..11899 + 669 WP_279283702.1 recombinase family protein -
NFK54_RS24275 (11926) 11926..12438 + 513 WP_063101691.1 molecular chaperone Tir -
NFK54_RS24280 (12537) 12537..13373 - 837 WP_279283703.1 DUF6430 domain-containing protein -
NFK54_RS24285 (13482) 13482..13664 + 183 Protein_14 resolvase -
NFK54_RS24290 (13743) 13743..13991 - 249 Protein_15 iron-containing alcohol dehydrogenase -
NFK54_RS24295 (14076) 14076..14699 - 624 WP_279283704.1 potassium channel family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..72595 72595
- inside IScluster/Tn - - 2587..11899 9312


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10940.41 Da        Isoelectric Point: 10.2004

>T248567 WP_279283701.1 NZ_CP099346:10009-10284 [Escherichia marmotae]
MSKWNIKFTRNGADDLNYWRDTDKKKFERIRQLLHSIEADPLTGIGKPERLRHHKDPALYSRRIDQSHRLVYSIQNGEII
IYAARYHYGEK

Download         Length: 276 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9288.45 Da        Isoelectric Point: 4.6364

>AT248567 WP_279283700.1 NZ_CP099346:9783-10028 [Escherichia marmotae]
MHAINFTDARKHFADTMKRVTDDAEPVRVMRRNAPDIVMIDAGEYEALIETVYLFSNPANAAHINESMKQAERGEFVEVE
Y

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References