Detailed information of TA system TA248556

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-sokC/Ldr(toxin)
• Location: 879588..879811
• Replicon: chromosome
• Accession: NZ_CP099344
• Organism: Escherichia marmotae strain RHB35-E2-C08

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: -
• Locus tag: NFK54_RS04545
• Protein ID: WP_222656830.1
• Coordinates: 879704..879811 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	sokC
Locus tag	-
Coordinates	879588..879654 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NFK54_RS04520	874868..876262	-	1395	WP_181502796.1	YchO/YchP family invasin	-
NFK54_RS04525	876446..876799	+	354	WP_001169672.1	DsrE/F sulfur relay family protein YchN	-
NFK54_RS04530	876843..877538	-	696	WP_016248767.1	glutathione-specific gamma-glutamylcyclotransferase	-
NFK54_RS04535	877696..877926	-	231	WP_001146437.1	putative cation transport regulator ChaB	-
NFK54_RS04540	878195..879295	+	1101	WP_279283463.1	sodium-potassium/proton antiporter ChaA	-
-	879588..879654	-	67	-	-	Antitoxin
NFK54_RS04545	879704..879811	+	108	WP_222656830.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
NFK54_RS04550	879991..880845	-	855	WP_000811071.1	3-deoxy-8-phosphooctulonate synthase	-
NFK54_RS04555	880881..881690	-	810	WP_001257034.1	invasion regulator SirB1	-
NFK54_RS04560	881694..882086	-	393	WP_222692457.1	invasion regulator SirB2	-
NFK54_RS04565	882083..882916	-	834	WP_000456440.1	peptide chain release factor N(5)-glutamine methyltransferase	-
NFK54_RS04570	882916..883998	-	1083	WP_279283464.1	peptide chain release factor 1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4001.77 Da
• Isoelectric Point: 11.4779

>T248556 WP_222656830.1 NZ_CP099344:879704-879811 [Escherichia marmotae]
MTLTQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT248556 NZ_CP099344:c879654-879588 [Escherichia marmotae]
TGTTTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTGACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin