Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 702690..702948 Replicon chromosome
Accession NZ_CP099338
Organism Escherichia fergusonii strain RHB44-C01

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag NFK94_RS03510 Protein ID WP_000809173.1
Coordinates 702690..702842 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 702891..702948 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK94_RS03490 697754..698341 + 588 WP_046083027.1 molybdopterin adenylyltransferase -
NFK94_RS03495 698375..698941 - 567 WP_000528529.1 acetate uptake transporter -
NFK94_RS03500 699449..701365 + 1917 WP_000516135.1 molecular chaperone DnaK -
NFK94_RS03505 701454..702584 + 1131 WP_001118464.1 molecular chaperone DnaJ -
NFK94_RS03510 702690..702842 - 153 WP_000809173.1 type I toxin-antitoxin system toxin MokC Toxin
- 702891..702948 + 58 - - Antitoxin
NFK94_RS03515 703383..704549 + 1167 WP_000681374.1 Na+/H+ antiporter NhaA -
NFK94_RS03520 704617..705516 + 900 WP_000019050.1 transcriptional activator NhaR -
NFK94_RS03525 705612..705875 - 264 WP_001274021.1 30S ribosomal protein S20 -
NFK94_RS03530 705978..706196 + 219 WP_012599853.1 DUF2575 family protein -
NFK94_RS03535 706204..707145 + 942 WP_000767324.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5487.54 Da        Isoelectric Point: 7.1312

>T248522 WP_000809173.1 NZ_CP099338:c702842-702690 [Escherichia fergusonii]
MKQHKAMIVALIVICVTAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT248522 NZ_CP099338:702891-702948 [Escherichia fergusonii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References