Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 702100..702358 Replicon chromosome
Accession NZ_CP099328
Organism Escherichia fergusonii strain RHB44-C21

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag NFL02_RS03495 Protein ID WP_197970443.1
Coordinates 702100..702252 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 702301..702358 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFL02_RS03475 697165..697752 + 588 WP_002431696.1 molybdopterin adenylyltransferase -
NFL02_RS03480 697786..698352 - 567 WP_000528529.1 acetate uptake transporter -
NFL02_RS03485 698860..700776 + 1917 WP_000516135.1 molecular chaperone DnaK -
NFL02_RS03490 700865..701995 + 1131 WP_001118464.1 molecular chaperone DnaJ -
NFL02_RS03495 702100..702252 - 153 WP_197970443.1 type I toxin-antitoxin system Hok family toxin Toxin
- 702301..702358 + 58 - - Antitoxin
NFL02_RS03500 702793..703959 + 1167 WP_000681374.1 Na+/H+ antiporter NhaA -
NFL02_RS03505 704027..704926 + 900 WP_000019049.1 transcriptional activator NhaR -
NFL02_RS03510 705022..705285 - 264 WP_001274021.1 30S ribosomal protein S20 -
NFL02_RS03515 705388..705606 + 219 WP_181198726.1 DUF2575 domain-containing protein -
NFL02_RS03520 705614..706555 + 942 WP_046081994.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T248465 WP_197970443.1 NZ_CP099328:c702252-702100 [Escherichia fergusonii]
MKQHKAMIVALIVICVTAIVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT248465 NZ_CP099328:702301-702358 [Escherichia fergusonii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References