Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 122674..123331 Replicon chromosome
Accession NZ_CP098926
Organism Halomonas sp. MS1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NF683_RS00545 Protein ID WP_095603866.1
Coordinates 122674..123018 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NF683_RS00550 Protein ID WP_193067530.1
Coordinates 123029..123331 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF683_RS00520 (NF683_00520) 118369..118770 - 402 WP_253921916.1 PaaI family thioesterase -
NF683_RS00525 (NF683_00525) 118833..119459 - 627 WP_125750324.1 LysE family translocator -
NF683_RS00530 (NF683_00530) 119746..121170 - 1425 WP_253920990.1 diguanylate cyclase -
NF683_RS00535 (NF683_00535) 121604..121891 - 288 WP_089039439.1 type II toxin-antitoxin system MqsA family antitoxin -
NF683_RS00540 (NF683_00540) 122042..122377 - 336 WP_089039441.1 zinc ribbon domain-containing protein YjdM -
NF683_RS00545 (NF683_00545) 122674..123018 + 345 WP_095603866.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF683_RS00550 (NF683_00550) 123029..123331 + 303 WP_193067530.1 XRE family transcriptional regulator Antitoxin
NF683_RS00555 (NF683_00555) 123399..125012 - 1614 WP_253920991.1 ABC-F family ATP-binding cassette domain-containing protein -
NF683_RS00560 (NF683_00560) 125224..126357 - 1134 WP_253920992.1 MFS transporter -
NF683_RS00565 (NF683_00565) 126502..127389 + 888 WP_253920993.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-89)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13203.03 Da        Isoelectric Point: 6.2305

>T248167 WP_095603866.1 NZ_CP098926:122674-123018 [Halomonas sp. MS1]
MWSIEQTDTFEAWFFSLEEIERENVLASVLLLRERGPMLSRPHADTVNGSQHSNMKELRVQCQGRPIRVFFAFDPRRTGI
LLCAGDKGGNDKRFYNEMIPVADKEYTAHLETLK

Download         Length: 345 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10964.76 Da        Isoelectric Point: 6.4757

>AT248167 WP_193067530.1 NZ_CP098926:123029-123331 [Halomonas sp. MS1]
MARKLEDLLAKEKPEIVAAAEAKANDMLFEIRLAEIRQLAEKTQADIAIAMGVKQPTVAGLEKVGQDMRLSSLKRYVEAL
GGRVRVDIELPDGSHHGFPV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References