Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5594122..5594719 Replicon chromosome
Accession NZ_CP098805
Organism Dyadobacter chenhuakuii strain CY22

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NFI80_RS23490 Protein ID WP_235164012.1
Coordinates 5594122..5594400 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag NFI80_RS23495 Protein ID WP_235164013.1
Coordinates 5594411..5594719 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFI80_RS23465 (NFI80_23465) 5589968..5590381 + 414 WP_235164008.1 type II 3-dehydroquinate dehydratase -
NFI80_RS23470 (NFI80_23470) 5590382..5592871 - 2490 WP_235164009.1 M14 family zinc carboxypeptidase -
NFI80_RS23480 (NFI80_23480) 5593308..5593559 - 252 WP_235164010.1 hypothetical protein -
NFI80_RS23485 (NFI80_23485) 5593671..5594015 + 345 WP_235164011.1 helix-turn-helix transcriptional regulator -
NFI80_RS23490 (NFI80_23490) 5594122..5594400 + 279 WP_235164012.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFI80_RS23495 (NFI80_23495) 5594411..5594719 + 309 WP_235164013.1 HigA family addiction module antitoxin Antitoxin
NFI80_RS23500 (NFI80_23500) 5595010..5595603 - 594 WP_235164014.1 hypothetical protein -
NFI80_RS23505 (NFI80_23505) 5595631..5595828 - 198 WP_235164015.1 hypothetical protein -
NFI80_RS23510 (NFI80_23510) 5595912..5597018 - 1107 WP_235164016.1 MBL fold metallo-hydrolase -
NFI80_RS23515 (NFI80_23515) 5597150..5599024 + 1875 WP_235164017.1 CocE/NonD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10886.47 Da        Isoelectric Point: 6.4829

>T248105 WP_235164012.1 NZ_CP098805:5594122-5594400 [Dyadobacter chenhuakuii]
MIESIQHKGLRLLFEEDNSSKLPPHLVERIREILSLLDVAETIEQLNVSGYRLHKLTGEFKDFYSIRVSGNYRIIFRFVD
GKVFDVNYLDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11244.88 Da        Isoelectric Point: 9.9233

>AT248105 WP_235164013.1 NZ_CP098805:5594411-5594719 [Dyadobacter chenhuakuii]
MLKRGMRPSHPGAILAGMIEGLREESGRAFTITEIAAGLGISRSTLSAILNQKASVSSEMAVKLSEGFNTSAELWLNLQK
NYDLWQAEKNVSRENIRHFVNV

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References