Detailed information of TA system TA247982

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 7279..7520
• Replicon: plasmid pEFM9-3
• Accession: NZ_CP098746
• Organism: Enterococcus faecalis strain M9

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: NDO76_RS13810
• Protein ID: WP_002360667.1
• Coordinates: 7410..7520 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	7279..7370 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NDO76_RS13790 (3004)	3004..4020	-	1017	WP_033593833.1	replication initiator protein A	-
NDO76_RS13795 (4683)	4683..5534	+	852	WP_002362419.1	ParA family protein	-
NDO76_RS13800 (5544)	5544..6086	+	543	WP_086321354.1	hypothetical protein	-
NDO76_RS13805 (6871)	6871..7170	-	300	WP_010817802.1	hypothetical protein	-
- (7279)	7279..7370	+	92	NuclAT_0	-	Antitoxin
- (7279)	7279..7370	+	92	NuclAT_0	-	Antitoxin
- (7279)	7279..7370	+	92	NuclAT_0	-	Antitoxin
- (7279)	7279..7370	+	92	NuclAT_0	-	Antitoxin
NDO76_RS13810 (7410)	7410..7520	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
NDO76_RS13815 (8015)	8015..8332	+	318	WP_002394802.1	heavy metal-binding domain-containing protein	-
NDO76_RS13820 (8368)	8368..9036	+	669	WP_002403283.1	CPBP family intramembrane metalloprotease	-
NDO76_RS13825 (9153)	9153..9407	+	255	WP_002394800.1	hypothetical protein	-
NDO76_RS13830 (9567)	9567..9800	-	234	WP_002394799.1	hypothetical protein	-
NDO76_RS13835 (9802)	9802..10113	-	312	WP_251846816.1	hypothetical protein	-
NDO76_RS13840 (10103)	10103..10723	-	621	WP_002367784.1	recombinase family protein	-
NDO76_RS13845 (11167)	11167..11817	-	651	WP_251846817.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	prgB/asc10	1..49313	49313

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T247982 WP_002360667.1 NZ_CP098746:c7520-7410 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT247982 NZ_CP098746:7279-7370 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin