Detailed information of TA system TA247970

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 474662..474888
• Replicon: chromosome
• Accession: NZ_CP098743
• Organism: Enterococcus faecalis strain M9

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: NDO76_RS02320
• Protein ID: WP_219843903.1
• Coordinates: 474662..474772 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	474683..474888 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NDO76_RS02310 (470094)	470094..472352	+	2259	WP_033627614.1	DNA helicase PcrA	-
NDO76_RS02315 (472478)	472478..474508	+	2031	WP_002358699.1	NAD-dependent DNA ligase LigA	-
NDO76_RS02320 (474662)	474662..474772	+	111	WP_219843903.1	putative holin-like toxin	Toxin
- (474683)	474683..474888	-	206	NuclAT_6	-	Antitoxin
- (474755)	474755..474890	-	136	NuclAT_14	-	-
- (474755)	474755..474910	-	156	NuclAT_8	-	-
NDO76_RS02325 (475090)	475090..475395	+	306	WP_002355569.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
NDO76_RS02330 (475395)	475395..476864	+	1470	WP_016615972.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-
NDO76_RS02335 (476864)	476864..478294	+	1431	WP_016615973.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	-
NDO76_RS02340 (478313)	478313..479401	+	1089	WP_002396964.1	diacylglycerol kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 3805.59 Da
• Isoelectric Point: 5.9482

>T247970 WP_219843903.1 NZ_CP098743:474662-474772 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 206 bp

>AT247970 NZ_CP098743:c474888-474683 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Structures

Antitoxin